All You Need to Know About UPNEEQ®

Has your eye doctor prescribed UPNEEQ® for your droopy eyelids, and you want to understand how this revolutionary treatment works? We have written this article to explain how this eye drop works and how you can use it to treat your acquired droopy eyelids!

Ways To Treat Droopy Eyelids

If you or a loved one is seeking to treat droopy eyelids, whether, for medical or cosmetic reasons, you are open to two treatment options: Eyelid Lift surgery and UPNEEQ®. UPNEEQ®, a second option to surgery, is the first treatment approved by the FDA to address droopy eyelids. But, how does it work?

How UPNEEQ® Works

UPNEEQ® is an eye drop that is inserted once per day, one drop per eye. This eye drop works by stimulating the Muller’s muscle to contract. In clinical trials, the mean amount of eyelid lift was 1 mm. Of course, this small lift won’t result in the dramatic result that comes with surgery. However, this small lift is beneficial medically and cosmetically to many patients.

How Long UPNEEQ® Lasts

In clinical trials, a dose of UPNEEQ® can stay active for at least six hours.

Is UPNEEQ® Safe And Effective?

Absolutely, yes! It is FDA-approved to be safe and effective for treating acquired eyelid ptosis. The primary ingredient in UPNEEQ® is the same main ingredient in decongestant nasal spray. The component in nasal spray stimulates the contraction of the blood vessels. However, the constituents in UPNEEQ® work to revive the contraction of the eyelid muscle.

The Side Effects Of UPNEEQ®

The side effects of UPNEEQ® include blurred vision, eye inflammation, headache, dry eye, redness, inflammation of the cornea, and conjunctival hyperemia. In addition, patients can experience eye pain moments after the application of the UPNEEQ® drops.

Is Everyone A Candidate For UPNEEQ®?

No! It is for individuals with:

  • Mild Eyelid Ptosis
  • Moderate Eyelid Ptosis
  • Severe Eyelid Ptosis

Also, these individuals must not be taking any medications that will interfere with the eye drop.


Are you considering UPNEEQ® for your eyelid ptosis now? Inform your ophthalmologist or board-certified cosmetic surgeon about your medications, medical history, and supplements that you are using. They will determine if you are a good fit for the procedure.

About Author

The Eye Center is the leading refractive practice in South Carolina, providing full service eye care and specializing in Refractive Surgery – Lasik, AST, PRK, PRELEX, as well as Corneal Transplant and Cataract Surgery.

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